故事描述腦神經專家Bennet Omalu發現橄欖球運動原因為腦部運動損傷（CTE）而造成對身體終其一生不可磨滅的傷害，他從這位在美國橄欖球史上有一席之地的Mike Webster自殺的遺體上，找到不曾公開的秘密，卻也是每個橄欖球球員無可迴避的事實，為了出人頭的，為了勝利，在賽場上無數次直接的腦部撞擊，對人體產生的後遺症，遠遠大出我們的了解。
Bennet Omalu不斷尋找答案，素有Iron Mike之稱的Mike Webster，偉大的球員最後的結局令人難以接受，他如何會智力衰減到最後自殘？而這個事實也是NFL想忽略。
This is the story of one man's fight against a multibillion dollar colossus. A man who stood up for what was right, whatever the cost.
The brilliant young forensic pathologist had no idea that the body on the slab in front of him would change his life, and ultimately change the world.
The body belonged to legendary American Footballer Mike Webster, whose mental health had rapidly declined after he had stopped playing - he had ended up Tasering himself to relieve his chronic back pain and fixing his rotting teeth with Superglue.
Dr Bennet Omalu found that the psychosis suffered by "Iron Mike" was no accident. His autopsy unearthed evidence of a trauma-related disease - the direct result of years of blows to the head in games. He knew it would keep killing scores of other sportsmen unless something was done. He believed that the NFL (National Football League), one of the most powerful corporations in America, would welcome the discovery. But it was the one truth they wanted to ignore.
Omalu himself became a target.
'This is classic David and Goliath stuff, and as exciting as a great courtroom drama. A riveting, powerful human tale . . . a masterclass on how to tell a story'
Charles Duhigg, New York Times columnist and bestselling author of The Power of Habit